World Journal of Clinical Medicine is an international, peer-reviewed open access journal dedicated to advancing research the field of clinical medicine. The journal provides a rapid publication process to ensure wide dissemination of high-quality articles to scientists, professionals, and interested individuals worldwide. Our goal is to serve as an efficient, reliable, and trusted platform for scholars and readers, publishing cutting-edge research in the field.
Abstract: Objective: To evaluate clinical efficacy of Banxia Baizhu Tianma (BBT) decoction in the treatment of patients with turbid phlegm blocking orifice (TPBO) syndrome of Alzheimer’s diseases (AD). Methods: The patients with TPBO syndrome of AD admitted to the Department of Neurology, Shandong Jvnan County Traditional Chinese Medicine Hospital from October 2021 to October 2022 were selected and randomly divided into the control group treated with conventional therapy including donepezil hydrochloride and the observed group combined with BBT decoction on the basis of control group for 8 weeks. The scores of Mini-Mental State Examination (MMSE), Montreal Cognitive Assessment (MoCA), Clinical Dementia Rating (CDR), Global Deterioration Scale (GDS), Activity of Daily Living Scale (ADL), Cohen-Mansfield Agitation Inventory (CMAI) and Traditional Chinese Medicine Syndrome Score (TCMSS) were estimated before and after treatment, so that to evaluate clinical efficacy. Results: Before treatment, no significant difference existed in the scores of above assessment indexes of patients between the two groups (P>0.05). After treatment, the scores of above assessment indexes of patients in the two groups were significantly improved than those before treatment (P<0.05), and which in the treatment group were significantly better than those (except for CDR) in the control group (P<0.05). So that the total effective rate in the treatment group was higher than that in the control group (P<0.05). Conclusion: BBT decoction could significantly improve the activity of daily living of patients with Alzheimer's disease by elevating the scores of various cognitive and learning and memory functions.Abstract: Objective: To evaluate clinical efficacy of Banxia Baizhu Tianma (BBT) decoction in the treatment of patients with turbid phlegm blocking orifice (TPBO) syndrome of Alzheimer’s diseases (AD). Methods: The patients with TPBO syndrome of AD admitted to the Department of Neurology, Shandong Jvnan County Traditional Chinese Medicine Hospital from Octob...Learn More
Abstract: Posterior lumbar interbody fusion (PLIF) is a classic lumbar fusion procedure in spine surgery. The internal fixation screws used in the fusion procedure are the key components that are used to fix the vertebrae to the fusion device. Based on CT slice data and human anatomy theory, the finite element model (FEM) of the L1-L5 lumbar region was reconstructed using the principle of reverse engineering. Taking the L3 segment vertebral body model as an example, the screw insertion plan during the operation was determined. Then, the finite element model of screw extraction was established using the finite element software. The fixation effect of the pedicle screw embedded in the vertebral body was discussed through the finite element analysis method and orthogonal experiments, as well as the factors influencing the fixation effect of the screw. The results show that the contact area between the internal fixation screws of intervertebral fusion surgery and the cortical bone has a significantly greater impact on the fixation strength than the contact area with the cancellous bone. Choosing screws with a higher pitch and a larger outer diameter can significantly enhance their fixation effect. After considering various influencing factors comprehensively. The preferred size of the screw is an outer diameter of 6.0 mm, a pitch of 1.75 mm, and an SSA angle of 0°. This provides a basis for the design of intervertebral fusion internal fixation screws and the insertion method.Abstract: Posterior lumbar interbody fusion (PLIF) is a classic lumbar fusion procedure in spine surgery. The internal fixation screws used in the fusion procedure are the key components that are used to fix the vertebrae to the fusion device. Based on CT slice data and human anatomy theory, the finite element model (FEM) of the L1-L5 lumbar region was recon...Learn More
