Clinical Medicine Frontiers is an international, peer-reviewed open access journal dedicated to advancing research the field of clinical medicine. The journal provides a rapid publication process to ensure wide dissemination of high-quality articles to scientists, professionals, and interested individuals worldwide. Our goal is to serve as an efficient, reliable, and trusted platform for scholars and readers, publishing cutting-edge research in the field.
Abstract: The effect of natural functional foods on oxidative stress in HIV-positive patients is summarized in this review, with particular attention to the implications for metabolic dysfunction-associated steatotic liver disease (MASLD). Since chronic liver disease, especially MASLD, is a prominent cause of death among HIV patients, the global prevalence of HIV continues to provide serious public health issues. Insulin resistance, lipid buildup, oxidative stress, and mitochondrial dysfunction are some of the many factors contributing to the pathophysiology of MASLD. In particular, oxidative stress interferes with regular cellular metabolism, resulting in fibrosis, inflammation, and hepatocellular cancer. Antioxidants have demonstrated promise in lowering oxidative stress and enhancing liver health. They can be found in various of functional foods, including salmon, pitaya, and specific plant-based and microbial sources. However, further research is needed to determine the precise therapeutic effects and mechanisms of action of these functional foods. Although there is encouraging evidence that antioxidant-active functional foods can help manage MASLD in persons living with HIV (PLWH), more thorough research is required to confirm their effectiveness and comprehend their underlying mechanisms.Abstract: The effect of natural functional foods on oxidative stress in HIV-positive patients is summarized in this review, with particular attention to the implications for metabolic dysfunction-associated steatotic liver disease (MASLD). Since chronic liver disease, especially MASLD, is a prominent cause of death among HIV patients, the global prevalence o...Learn More
Abstract: Three-dimensional (3D) reconstruction technology, as a vital component of digital medicine, has emerged as a powerful tool in the field of hepatic surgery, particularly in the context of precision liver resection. This review examines the current applications and future prospects of 3D reconstruction technology in hepatic surgery, with a focus on its clinical progress in preoperative assessment, vascular protection, surgical planning, and intraoperative navigation. By accurately calculating liver volume, evaluating liver function reserves, and optimizing surgical strategies, 3D reconstruction significantly enhances the safety and efficacy of liver resection. In terms of vascular protection, 3D reconstruction enables precise localization of tumors relative to vascular structures and identification of vascular variations, thereby reducing intraoperative bleeding risks. For surgical planning, the integration of 3D reconstruction with virtual reality (VR) and augmented reality (AR) technologies allows for the creation of virtual surgical scenarios, optimization of surgical pathways, and reduction of operative time. In intraoperative navigation, 3D reconstruction combined with laparoscopic ultrasound, indocyanine green (ICG) fluorescence imaging, 3D printing, and mixed reality (MR) technologies has enabled real-time navigation, thereby improving surgical precision. Despite these advancements, 3D reconstruction technology still faces challenges, including high costs, time-consuming processes, data quality limitations, and suboptimal reconstruction of intrahepatic bile ducts. Looking ahead, the incorporation of artificial intelligence and big data into 3D reconstruction is expected to further refine preoperative planning and intraoperative navigation, driving the field of hepatic surgery toward greater intelligence and precision.Abstract: Three-dimensional (3D) reconstruction technology, as a vital component of digital medicine, has emerged as a powerful tool in the field of hepatic surgery, particularly in the context of precision liver resection. This review examines the current applications and future prospects of 3D reconstruction technology in hepatic surgery, with a focus on i...Learn More
