Research on the Bactericidal and Antiseptic Effect of Highly Efficient Compounded Thiabendazole
1. The Key Laboratory of Biotechnology for Medicinal Plant of Jiangsu Province, School of Life Science, Jiangsu Normal University, Xuzhou 221116, China
2. Jiangsu Noon Crop Science Co., Ltd., Xuzhou 221116, China
| Abstract: | The extensive use of traditional chemical pesticides can have an impact on human health. On the other hand, biopesticides have the advantages of having fewer side effects on the human body and being generally more beneficial to health. In order to reduce the use of the chemical pesticide thiabendazole, cinnamaldehyde, an active plant extract, is compounded with thiabendazole to form a new type of low - toxicity biopesticide fungicide and preservative, and its fungicidal and preservative effects are studied. A large number of antibacterial experiments show that when the ratio of thiabendazole to cinnamaldehyde is 5 mg/L:0.05 g/L, it has a good inhibitory effect on Mucor and yeast, and when the ratio is 5 mg/L:0.15 g/L, it has a better inhibitory effect on Aspergillus niger. Through the analysis of the antibacterial experiments, the composite concentration ratio of thiabendazole:cinnamaldehyde of 5 mg/L:0.15 g/L is selected, and based on this ratio, the experimental agent CAT (cinnamaldehyde and thiabendazole) is prepared. After compounding, greenhouse experiments are carried out. A large number of greenhouse experiment results show that the inhibitory effect of the compounded agent is not lower than that of the thiabendazole agent used alone. The research results provide a research basis for reducing the use of thiabendazole and developing new - type, high - efficiency and low - toxicity biopesticide preservatives. Through greenhouse experiments and cooperation with enterprises, the research also proves that this experimental agent is suitable for industrial production. |
| Keywords: | Biopesticides; Highly Effective and Low Toxicity; Broad-spectrum Antibacterial Activity; Formulation |
| DOI: | 10.57237/j.jaf.2024.04.003 |
View:
Downloads:
收稿日期: 2024-10-09
接受日期: 2024-11-19
在线出版日期: 2024-12-05
参考文献
| [1] | Kumar, Vinod, et al. "Integrated Omics Approaches for Plant Disease Resistance." Biotechnological Advances for Disease Tolerance in Plants. Singapore: Springer Nature Singapore, 2024. 211-237. |
| [2] | Dhuldhaj UP, Singh R, Singh VK. Pesticide contamination in agro-ecosystems: toxicity, impacts, and bio-based management strategies. Environmental Science and Pollution Research. 2023, 30(4): 9243-70. |
| [3] | Qiu, D. W., Analysis of the Development Situation and Trends of Biological Pesticides in China [J]. journal 1, 2015, 31(5): 679-684. |
| [4] | Fan, X., Yang T., Wang Y. Y., et al. Preparation and Application of Electrospun Zein-Cinnamaldehyde Fruit Freshness Preservation Films [J]. Food Research and Development, 2024, 45(05): 1-7. |
| [5] | Zheng, X., Ding, L., Chen, Z., Guo, J., et al. Rapid determination of thiabendazole and triabendazole in concentrated fruit juices by ultra-high performance liquid chromatography-tandem mass spectrometry [J]. Chinese Journal of Chromatography, 2015, 33(6): 652-656. |
| [6] | Doyle AA, Stephens JC. A review of cinnamaldehyde and its derivatives as antibacterial agents. Fitoterapia. 2019, 139: 104405. |
| [7] | Shreaz S, Wani WA, Behbehani JM, et al. Cinnamaldehyde and its derivatives, a novel class of antifungal agents. Fitoterapia. 2016, 112: 116-31. |
| [8] | Ji, Y., Wang, J., Liu, Y., et al. Isolation and Identification of Postharvest Rot Pathogens in Citrus× tangelo and Their Potential Inhibition with Acidic Electrolyzed Water. Food and Environmental Virology. 2024: 1-13. |
| [9] | Jiang, Y., Liu, X., Zhuang, Z., et al. Impact of government subsidy strategies on bio-pesticide supply chain considering farmers' environmental safety preferences. Clean Technologies and Environmental Policy. 2024: 1-9. |
| [10] | Zhang, A., Lai, H. J., Liu, R., et al. Determination of Thiourea Residue in triabendazole [J]. Guangdong Chemical Industry, 2021, 48(14): 204-206. |
| [11] | Luan, J., Bai, X., Liu, Y., et al. PVA /PDA@g-C3N4 Composite Nanofiber Membranes for Enhanced Photocatalytic Bacteriostasis and Degradation. J Polym Environ, 2024, 32: 1796–1810. |
| [12] | Shen, S., Zhang, T., Yuan, Y., et al. Effects of cinnamaldehyde on Escherichia coli and Staphylococcus aureus membrane. Food control. 2015, 47: 196-202. |
| [13] | Leesutthiphonchai W, Piasai O, Vajrodaya S, et al. Evaluation of efficacy of four Cinnamomum species extracts and cinnamaldehyde to control anthracnose of mango fruit. European Journal of Plant Pathology. 2024: 1-7. |
| [14] | Dou, X. Y., Hu, X., Feng, Z. Y., et al. Research Progress on the Control of Foodborne Pathogens and Their Biofilms by Cinnamaldehyde [J/OL]. Food Science. 2024: 1-20. |
