基于中医传承辅助系统治疗慢性萎缩性胃炎用药规律分析
1. 广西中医药大学, 赛恩斯新医药学院, 广西南宁 530000
2. 广西中医药大学, 基础医学院, 广西南宁 530000
| 摘 要： | 目的：运用中医传承辅助系统探索治疗慢性萎缩性胃炎（Chronic Atrophic Gastritis, CAG）方剂的用药及组方配伍规律。方法：检索中国期刊全文数据库（CNKI）中治疗慢性萎缩性胃炎的相关文献，检索时限2008至2018年。应用中医传承辅助系统建立相应数据库，以挖掘高频药对、新方组合为目的，以方论证，总结近十年来的临床用药经验，为中医治疗CAG寻找新突破。结果：经筛选得出符合纳入标准的方剂223首，包含中药217味，统计结果显示，在治疗CAG的常用药物中以补气健脾药为主；党参-白术药对最为常见；关联规则分析显示白术与它药的关联最多；重新归纳总结了6首新方。结论：经数据挖掘统计分析，所选数据库中收录的治疗CAG的方剂以健脾和胃、调畅气机、温中补虚、活血通络、滋阴养胃、清热祛湿等功效为主，为中医临床治疗CAG开展了新思路。 |
| 关 键 词： | 慢性萎缩性胃炎; 中医传承辅助系统; 组方配伍规律分析 |
| DOI： | 10.57237/j.cmrd.2023.02.003 |
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收稿日期: 2023-02-28
接受日期: 2023-04-27
在线出版日期: 2023-05-25
Analysis of Medication Law in Treatment of Chronic Atrophic Gastritis Based on TCM Inheritance Auxiliary System
1. Faculty of Chinese Medicine Science, Guangxi University of Chinese Medicine, Nanning 530000, China
2. Basic Medicine College, Guangxi University of Chinese Medicine, Nanning 530000, China
| Abstract: | Object: The use of traditional Ghinese Medicine Inheritance assistance system (TMC) for the treatment of chronic atrophic gastritis prescription and the rule of compatibility. Methods: Computer - based Retrieval of Chinese journal full-text database (CNKI) for the treatment of chronic atrophic gastritis related literature, search time limit: 2008-2018. In order to explore the combination of high frequency drug pairs and new prescriptions, the database was established with the aid of traditional Chinese medicine inheritance system. The purpose of this paper was to demonstrate the clinical experience of traditional Chinese medicine in the past ten years, and to find a new breakthrough for the treatment of CAG in traditional Chinese medicine. Result: After screening 223 prescriptions that met the inclusion criteria, including 217 herbs of traditional Chinese medicine, the statistical results show that in the treatment of CAG, the main medicine is invigorating qi and invigorating spleen and Codonopsis and Atractylodes macrocephala are the most common. Combined rule analysis showed that Atractylodes macrocephala had the most association with other drugs. The six new formulas are summarized again. Conclusion: Through the data mining statistical analysis, the prescription of treating CAG included in the selected database is mainly invigorating spleen and stomach, regulating qi, warming and tonifying deficiency, activating blood circulation, nourishing yin and nourishing stomach, clearing heat and dispelling dampness and so on. It has developed a new way of thinking for the clinical treatment of CAG in traditional Chinese medicine. |
| Keywords: | Chronic Atrophic Gastritis; TCM Inheritance System; Composition and Compatibility Principle |
基金
| 1. | 广西中医药大学赛恩斯新医药学院科研项目 (2022MS002, 2022MS008, 2022QJ001) |
| 2. | 广西中医药大学项目 (2022MS024, 2022QN008) |
| 3. | 广西中医药大学赛恩斯新医药学院国家级大学生创新创业训练项目 (202113643014) |
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