女性肿瘤患者生育力保存技术现状和进展
昆明医科大学, 第一附属医院生殖遗传科, 云南昆明 650032
| 摘 要： | 众所周知肿瘤的患病率不断增高，随着医学检查和治疗手段的发展，肿瘤在年轻女性中的检出率和治愈率也逐渐升高，在实现“保命”这一基本生存需求后不少的患者仍然想实现为人父母的梦想。然而疾病本身的进展以及放化疗等治疗手段都会对患者的生育力造成不可逆的损伤，因此，对于这部分患者及时尽早的生育力保存尤为重要。生育力保存在中国方兴未艾，肿瘤患者就是其主要的指征之一。近年来该技术取得重大进展，目前成熟的技术包括卵巢组织冻存和移植、卵子和胚胎冷冻等，因医生缺乏对具体方案的了解和运用导致很多患者错失生育力保存的时机，为了给患者提供更科学的生育力保存方案，本文结合近年来国内外女性肿瘤患者生育力保存相关研究，对目前女性肿瘤患者生育力保存的方案及其进展做一综述。 |
| 关 键 词： | 女性肿瘤; 生育力保存; 卵巢组织冻存; 卵子冷冻; 胚胎冷冻 |
| DOI： | 10.57237/j.cmf.2023.01.001 |
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收稿日期: 2022-09-30
接受日期: 2022-11-04
在线出版日期: 2023-05-25
Fertility Preservation in the Female Tumor Patients
Department of Reproduction and Genetics, the first affiliated hospital of Kunming Medical University, Kunming 650032, China
| Abstract: | As we all know, the prevalence of tumors is increasing, and with the development of medical examination and treatment methods, the detection rate and cure rate of tumors in young women are gradually increasing, and many patients still want to realize their dream of parenthood after realizing the basic survival need of "saving life". However, the progression of the disease itself and treatment methods such as radiotherapy and chemotherapy will cause irreversible damage to the fertility of patients, so it is particularly important for these patients to preserve fertility as soon as possible. Fertility preservation is in the ascendant in China, and tumor patients are one of its main indications. In recent years, the technology has made significant progress, the current mature technology includes ovarian tissue cryopreservation and transfer, egg and embryo freezing, etc., due to the lack of understanding and application of specific programs by doctors, many patients miss the opportunity of fertility preservation, in order to provide patients with more scientific fertility preservation programs, this paper combines the fertility preservation related research of female tumor patients at home and abroad in recent years, and reviews the current fertility preservation programs and progress of female tumor patients. |
| Keywords: | Female Tumor; Fertility Preservation; Ovarian Tissue Cryopreservation; Oocyte Cryopreservation; Embryo Cryopreservation |
基金
| 1. | 云南省高层次人才培养职称计划“名医专项” (RLMY20200017) |
| 2. | 国家自然科学基金项目 (82160281) |
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