The Study on the Antibacterial Effects of Several Traditional Chinese Medicines
College of Life Sciences, Southwest Forestry University, Kunming 650224, China
| Abstract: | Objective: The effective components of Fructus Aurantii, Pulsatilla chinensis, Schisandra chinensis, Sanguisorba officinalis, Scutellaria baicalensis, Terminalia chebula, Rheum officinale, Punica granatum, Fructus Mume, Cortex Phellodendri and Coptis chinensis were extracted, and the minimum inhibitory concentrations of components from these Traditional Chinese Medicines were analyzed in vitro against Staphylococcus chromogenes, S. xylosus, S. pseudintermedius, Yokenella regensburgei, Aeromonas hydrophila and Klebsiella pneumoniae, so as to lay a theoretical foundation for the application and development of Traditional Chinese Medicine in clinical treatment. Methods: The effective components of Traditional Chinese Medicines were extracted by alcohol extraction, and the minimal inhibitory concentration of single Traditional Chinese Medicine was determined by tube dilution method. Results: S. chinensis, P. granatum, F. Mume and T. chebula showed the most significant bacteriostatic effects on S. xylosus (MICs were all 62.50 mg/mL); S. chinensis presented the most significant antibacterial effect on S. chromogenes (MIC was 31.25 mg/mL); S. chinensis, P. granatum and T. chebula had the most significant bacteriostatic effects on S. pseudointermedia (MICs were all 31.25 mg/mL); S. chinensis, S. officinalis, T. chebula, R. officinale, F. Mume and C. chinensis had the most significant bacteriostatic effects on Y. regensburgei (MICs were all 15.60 mg/mL); The inhibitory effect of S. officinalis on A. hydrophila was the most significant (MIC was 1.95 mg/mL); F. Mume had the most significant antibacterial effect on K. pneumoniae (MIC was 0.98 mg/mL). Conclusion: S. chinensis, F. mume and T. chebula et al. have good antibacterial effects, thus providing basis for the clinical application of these Traditional Chinese Medicines. |
| Keywords: | Traditional Chinese Medicine; Strains; Minimum Inhibitory Concentration; Antibacterial Effects |
| DOI: | 10.57237/j.life.2022.01.004 |
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Received: 8 December 2022
Accepted: 7 March 2023
Published Online: 28 March 2023
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